| 書(shū)目名稱(chēng) | MicroRNA Expression Detection Methods | | 編輯 | Zhiguo Wang,Baofeng Yang | | 視頻video | http://file.papertrans.cn/633/632801/632801.mp4 | | 概述 | Gives comprehensive descriptions of miRNA expression detection methods.Shows applications of miRNA profiling in miRNA research.Highlights the potential of miRNA profiling in clinical diagnosis and pro | | 圖書(shū)封面 |  | | 描述 | MicroRNAs (miRNAs), endogenous noncoding regulatory mRNAs of - nucleotides, have rapidly emerged as the central players in gene expression regulation. Owing to their ever-increasing implications in the control of various biological and pathological processes, miRNAs have now been considered novel biomarkers of various human diseases including, cancer, viral disease, cardiov- cular disorders, metabolic disturbances, etc. Particular expression pro?les have been associated with particular pathological states. Expression pro?ling of miR- NAs have therefore become extremely important not only for fundamentalists but also for clinicians. However, the methodologies used for detecting protein-coding mRNAs cannot be directly applied to miRNAs because of their small size. Over the past years, researchers have made great efforts to developing techniques suitable for miRNA detection and quanti?cation; a wide spectrum of creative and inno- tive techniques (more than 30 different methods) have been invented and validated. It has come to the time now to summarize these methods and present them in an orderly manner for better understanding and utilization of these methods to miRNA research and app | | 出版日期 | Book 2010 | | 關(guān)鍵詞 | FISH; Ligation; Microarray; PCR; gene expression; gene therapy; genes; hybridization; miRNA; miRNA detection; | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-04928-6 | | isbn_softcover | 978-3-642-42518-9 | | isbn_ebook | 978-3-642-04928-6 | | copyright | Springer-Verlag Berlin Heidelberg 2010 |
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