Titlebook: Metronomic Chemotherapy; Pharmacology and Cli Guido Bocci,Giulio Francia Book 2014 The Editor(s) (if applicable) and The Author(s), under e

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Lisa Salvatore,Federica Zoratto,Fotios Loupakis,Alfredo Falconerliegende Beitrag untersucht die Validit?t der darauf aufbauenden Messinstrumente am Beispiel des T.-M.s. Mithilfe dieser einzigartigen L?ngsschnittstudie werden für einen Zeitraum von zwei Jahrzehnten die interne Struktur und Entwicklung der Messung und des Ph?nomens ?Rechtsextremismus‘ analysiert.

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https://doi.org/10.1007/978-3-662-43604-2Antiangiogenic drugs; Cancer; Metronomic chemotherapy; Pharmacology

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Guido Bocci,Giulio FranciaCovers all aspects of metronomic chemotherapy.Describes the pharmacological bases of metronomic chemotherapy.Presents and discusses the clinical results of all published studies on metronomic chemothe

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The Role of Metronomic Chemotherapy in the Treatment of Metastatic Colorectal Cancer Patients or partial antiangiogenic activity such as bevacizumab, aflibercept, and regorafenib. Metronomic chemotherapy may be an alternative strategy for targeting tumor angiogenesis and several clinical studies suggested its promising activity and its extremely favorable toxicity profile in the treatment of metastatic colorectal cancer patients.

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Mechanisms of Action of Low-Dose Metronomic Chemotherapyction. Initially, LDM was considered an antiangiogenic treatment strategy; however, in the last decade additional preclinical studies uncovered other possible mechanisms including enhancing the antitumor immune response, substantially increasing the efficacy of targeted drugs by various mechanisms,

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Effects of Metronomic Chemotherapy on Immunity-bearing hosts. However, administration protocols heavily influence the host’s immunity because chemotherapeutic agents potentially kill proliferating lymphocytes. To this end, we investigated the effects of a CTX administration protocol on the in vivo induction of antitumor T cells in a preclinical