| 書目名稱 | Methods in Membrane Biology | | 副標(biāo)題 | Volume 7 | | 編輯 | Edward D. Korn | | 視頻video | http://file.papertrans.cn/633/632310/632310.mp4 | | 圖書封面 |  | | 描述 | The contributions of electron microscopy to membrane biology have been indispensable and, at the same time, disappointing. Membranes were known to exist before the advent of electron microscopy and general principles of their composition and molecular organization had been deduced from permeability and electrical conductivity measurements, polarized light microscopy, and X-ray diffraction. On the other hand, the complexities of the many intracellular membranes and membranous organelles were really not suspected until they were observed by the electron microscopist. One then had further hopes that the high resolution of the electron microscope (theoretically it can resolve atomic distances) would allow the visualization of the molecular architecture of membranes and lead directly to an under- standing of structure and function at the molecular level. This expectation has been largely unrealized. Because of the great difficulties encountered in the preparation of biological material, because of the uncertainty of the chemistry of "staining," and because of numerous electron optical artifacts, it has been a major challenge just to rationalize the observed images in terms of the known | | 出版日期 | Book 1976 | | 關(guān)鍵詞 | X-ray; biological; biological membranes; biology; carbohydrates; chemistry; diffraction; electron; electron | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4757-5820-7 | | isbn_softcover | 978-1-4757-5822-1 | | isbn_ebook | 978-1-4757-5820-7 | | copyright | Springer Science+Business Media New York 1976 |
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