Titlebook: Methods in Membrane Biology; Volume 9 Edward D. Korn Book 1978 Plenum Press, New York 1978 biochemistry.biology.chemistry.electron microsco

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is as necessary as it is rigorous, and it should long be the standard in this area of research. The second chapter in this volume is a more specialized review by Matus of the procedures for the preparation and characterization of the highly differentiated junctional regions of brain plasma membranes. These m978-1-4613-4038-6978-1-4613-4036-2

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Synaptic Membranes and Junctions from Brain, intact form as subcellular particles or . (Gray and Whittaker, 1962; De Robertis .., 1962). When examined in the electron microscope, synaptosomes exhibit many of the same morphological features by which synapses in intact tissue are recognized (see Fig. 1). The . appears as a closed sac of plasma

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