Titlebook: Metabolic Changes Induced by Alcohol; G. A. Martini,Ch. Bode Book 1971 Springer-Verlag Berlin · Heidelberg 1971 cancer.central nervous sys

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Extrahepatic Oxidation of Alcohol and Alcohol Metabolitesed in 1910. They found that the liver from many species of animal has a high capacity for metabolizing alcohol, but that to some extent the kidneys could also perform the oxidation. Their investigations were carried out using minced tissue preparations. In the same year, HAMILL (1910) showed that a

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Studies on the Inhibitory Effect on Ethanol Oxidation in Man After Administration of 4-Methylpyrazol understanding of the biochemical aspects of alcoholism. Recently BLOMSTRAND et al. (1,2) were able to establish distinct excretion patterns of .CO. in expired air in man after the administration of only 2 μC of ethanol-1-.C or ethanol-2-.C, thus enabling several consecutive studies with labelled et

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Effect of Ethanol on the Activity of Microsomal Enzymesmore, NADH generation (either by ethanol or acetaldehyde oxidation) offers a satisfactory explanation for a number of biochemical effects produced by ethanol, including increased lipogenesis (LIEBER, C.S. et al., 1959; LIEBER, C.S. and SCHMID, R., 1961; NIKKILA, E. and OJALA, K., 1963), decreased li

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Interaction between Ethanol Oxydation and Drug Metabolismo convert a wide variety of compounds into more polar (i.e., hydroxylated or dealkylated) derivatives. In our studies the increased oxygen uptake of perfused liver following the addition of a suitable substrate, e.g., aminopyrine, was used to estimate the rate of this microsomal process (1).