Titlebook: Meningococcal Vaccines; Methods and Protocol Andrew J. Pollard,Martin C.J. Maiden Book 2001 Springer Science+Business Media New York 2001 i

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1543-1894 molecular tools with which to lay bare the secrets of the meningococcus. The results of this ambitious and welcome v- ume represent an exciting and much needed resource for all of us in the field.978-1-4899-4225-8978-1-59259-148-0Series ISSN 1543-1894 Series E-ISSN 1940-6037

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Book 2001am of experts gathered by Andy Pollard and Martin Maiden converge to p- vide an impressive accumulation of molecular tools with which to lay bare the secrets of the meningococcus. The results of this ambitious and welcome v- ume represent an exciting and much needed resource for all of us in the field.

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Immune Response and Host-Pathogen Interactions,ife is an almost universal experience but clinically overt disease is unusual except during epidemics. This overview considers the relationship between the meningococcus and humans, reviewing current immunological and molecular understanding of this interaction of relevance to development of immunog

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Methods for the Preparation and Crystallization of Fab Fragments in Complex with Peptide Antigens D more rational approach to vaccine design. X-ray crystallography has been outstandingly successful in delineating the detailed chemical interactions that are responsible for the high affinity and high selectivity of antibody-antigen interactions (.). Although a number of X-ray structures of OMPs hav

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