Titlebook: Membrane Protein Complexes: Structure and Function; J. Robin Harris,Egbert J. Boekema Book 2018 Springer Nature Singapore Pte Ltd. 2018 Ba

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Ryanodine Receptor Structure and Function in Health and Disease,eletal muscle, synaptic transmission in the brain, pancreatic beta cell function, and vascular tone. In disease, defective function of RyRs due either to stress (hyperadrenergic and/or oxidative overload) or genetic mutations can render the channels leaky to Ca. and promote defective disease-causing

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Conformational Equilibrium of Human Platelet Integrin Investigated by Three-Dimensional Electron Crl studies for many years, in particular using X-ray crystallography, nuclear magnetic resonance spectroscopy, and two-dimensional negative stain electron microscopy. Despite considerable progress, a full consensus on the molecular mechanism of integrin activation is still lacking. Three-dimensional

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Microbial Rhodopsins,tly found a great application as optogenetic tools. While the basic aspects of microbial rhodopsins functioning have been known for some time, there is still a plenty of unanswered questions. This chapter presents and summarizes the available knowledge, focusing on the functional and structural studies.

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