Titlebook: Melanin Chemistry Explored by Quantum Mechanics; Investigations for M Ryo Kishida,Susan Me?ez Aspera,Hideaki Kasai Book 2021 The Editor(s)

Servile

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Jocose

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Concluding Remarks and Future Perspectives,Summarizing our findings, we give concluding remarks and future perspectives. One of next challenges will be to unveil quantum effects of atomic nuclei in melanogenesis. While the classical description of atomic nuclei is sufficient for most scenarios, certain phenomena require quantum mechanical description of both atomic nuclei and electrons.

口訣法

n the pigmentary system.Discusses theoretical and experimentThis book discusses recent advances in theoretical–computational studies on the biosynthesis of melanin pigment (melanogenesis). These advances are being driven by the development of high-performance computers, new experimental findings, an

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Asperity

樹木中

虛構(gòu)的東西

Dopachrome Conversion,nation of the quinonoid group of dopachrome. The catalytic effects of basic pH and Cu(II), experimentally observed, can be explained based on two aspects: (i) promotion of the rate-determining step, namely β-deprotonation and (ii) protection of quinonoid group from protonation. Our approach clarifie

蔓藤圖飾

Dopaquinone Conversion and Related Reactions,quinone are pointed out as important factors affecting the reactivity and the competition between the two reactions. Furthermore, a mechanistic issue of thiol binding is also discussed based on the atomic-scale simulation results, which showed the presence of unusual reaction intermediate. Our appro

使迷醉

lting melanin pigment by means of competitive reactions. The book also addresses reactions analogous to melanogenesis, with a focus on o-quinone reactions, which are especially important for understanding melanogenesis-associated cytotoxicity..978-981-16-1317-3978-981-16-1315-9