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Titlebook: Mechanisms of Receptor Regulation; George Poste,Stanley T. Crooke Book 1985 Plenum Press, New York 1985 Antigen.cancer.catecholamines.drug

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發(fā)表于 2025-3-23 10:00:12 | 只看該作者
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發(fā)表于 2025-3-23 14:27:02 | 只看該作者
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發(fā)表于 2025-3-23 21:35:33 | 只看該作者
Sorting and Recycling of Cell Surface Receptors and Endocytosed Ligands, the cell surface followed by internalization of the complex into endocytic vesicles. During this process, ligand-receptor dissociation occurs, most probably in a low-pH prelysosomal compartment. In most cases, the ligand is ultimately directed to the lysosomes, wherein it is degraded, while the rec
14#
發(fā)表于 2025-3-24 00:23:09 | 只看該作者
The Nicotinic Acetylcholine Receptor,olubilization (see Conti-Tronconi and Raftery, 1982). Purified membrane fragments can reseal, forming closed, right-side-out vesicles, which can be used for both functional and structural studies. The major physiochemical properties of . AcChR protein are summarized in Fig. 1.
15#
發(fā)表于 2025-3-24 05:34:20 | 只看該作者
,Adenylate-Cyclase-Coupled β- Adrenergic Receptors, leads to the generation of the second messenger, cAMP, which initiates a cascade of events responsible for the ultimate response to that particular hormone. Catecholamines such as epinephrine and norepinephrine and various polypeptide hormones such as ACTH, glucagon, LH, and FSH are examples of hor
16#
發(fā)表于 2025-3-24 10:09:39 | 只看該作者
Control of Receptor Function by Homologous and Heterologous Ligands,e biological effect (e.g., trypanocidal dyes) could bind to receptors that display a strict chemical specificity to react with one family of compounds but not another. This fundamental concept formed the basis of work that led to the clear-cut distinction among receptors for agents such as histamine
17#
發(fā)表于 2025-3-24 13:59:19 | 只看該作者
18#
發(fā)表于 2025-3-24 15:37:44 | 只看該作者
Unique Tumor-Specific Antigens as Altered Cell-Surface Receptors,leus of the malignant cells. Interestingly, however, many of the products of cancer-inducing viral genes-so called oncogenes-have now been traced to the periphery of the cell, namely, the plasma membrane. Furthermore, several of these viral oncogenes appear to be derived from cellular genes that cod
19#
發(fā)表于 2025-3-24 21:40:47 | 只看該作者
Bert W. O’Malleytional scientists.Also available online in www.springerLink..The volume "Observed Global Climate" comprises a set of climate budget quantities, relevant for atmosphere and ocean (the "climate fluids") as well as for land and ice (the "climate solids"). Examples for budget quantities are temperature,
20#
發(fā)表于 2025-3-25 00:05:30 | 只看該作者
Michael J. Berridges for land and ice (the "climate solids"). Examples for budget quantities are temperature, salinity, wind, rain, radiation. They are displayed in standardised form for all climate subsystems. ..The data are arranged around the budget principle which is basic for the entire climate system. The book d
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