Titlebook: Mechanisms of Drug Resistance in Cancer Therapy; Mario Mandalà,Emanuela Romano Book 2018 Springer Nature Switzerland AG 2018 Drug resistan

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Mechanisms of Resistance in Multiple Myeloma,medullary sites. Multi-modality approaches including “novel agents,” traditional chemotherapy, and/or stem cell transplantation are used in MM therapy. Drug resistance, however, ultimately develops and the disease remains incurable for the vast majority of patients. In this chapter, we review both t

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Mario Mandalà,Emanuela RomanoGives an updated overview on the possible reasons of failure of new and promising therapeutic opportunities.Provides extensive discussions of issues including pharmacodynamic and pharmacokinetic mecha

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Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/m/image/628714.jpg

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https://doi.org/10.1007/978-3-030-10507-5Drug resistance; Drug mechanisms; Targeted therapy; Immunotherapy; Chemotherapy; antibacterial drug resis

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Springer Nature Switzerland AG 2018

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Book 2018 rational therapeutic drug combinations and the use of predictive and prognostic biomarkers to enable patient stratification and tailor treatments. It offers to the readers an updated overview on the possible reasons of failure of new and promising therapeutic opportunities..

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Major Physiological Signaling Pathways in the Regulation of Cell Proliferation and Survival,research have suggested that the intrinsic pro-survival signaling crosstalk is the driving force in acquired resistance to a targeted therapy, which may be abolished by interfering with the cross-reacting network.

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