Titlebook: Mechanism of Action of Antibacterial Agents; Fred E. Hahn Book 1979 Springer-Verlag Berlin · Heidelberg 1979 Antibiotikum.Biosynthese.Chem

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果仁

Chloramphenicol,rds, its structure was elucidated and it became the first antibiotic to be synthesized by chemical means (. et al., 1949). The chemical structure of chloramphenicol is given in Fig. 1. It is one of the rare natural compounds which carry a nitro group. Nevertheless, the molecule has a structure which

脆弱吧

Ethambutol,diisopropylethylenediamine (Fig. 1) was highly active against members of the genus ., particularly against . both in vitro and in experimentally infected mice (. and ., 1962; . et al., 1966). These observations were both exciting and intriguing, since the chemical structure of this compound was comp

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大廳

Kidamycin and Acetyl Kidamycin,mycin proposed to reduce toxicity (., 1972). While weakly active against some microorganisms, these drugs inhibit the multiplication of some transplantable animal tumors and exhibit considerably high cytotoxic activity against normal and neoplastic cells.