Titlebook: Mathematik für das Bachelorstudium III; Funktionentheorie, M Mike Scherfner,Torsten Volland Textbook 2023 Springer-Verlag GmbH Deutschland,

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Mike Scherfner,Torsten Vollandd genomic sequences involved in the mechanisms of neoplastic transformation, developmental regulation, physiological processing, pathological disorder, and therapeutic efficacy. Subtractive hybridization between two complementary DNA (cDNA) libraries is a powerful tool for identifying differentially

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a glass microscope slide, this tool can carry thousands of DNA fragments in an area smaller than a postage stamp. In this chapter, we will describe microarray chips that host nucleic acid probes, which are the most commonly used type of microarrays. Science in this field is mostly data-driven, where

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Mike Scherfner,Torsten Vollandare present in the precursor mRNA (pre-mRNA) molecule and subsequent ligation of the flanking, functional sequences (i.e., exons). Pre-mRNA splicing is thus a critical step in the long chain of events required for the expression of a large number of eukaryotic genes. In a number of instances, the sp

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Mike Scherfner,Torsten Vollandup of enzymes makes use of a free radical mechanism to produce deoxyribonucleotides, a reaction essential to all life on earth, contemporary as well as primordial. Ribonucleotide reductases belong to a heterogeneous family of enzymes, containing at least three discernible classes. They differ in com

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Mike Scherfner,Torsten Vollandmeter which describes this constraint is the linking number (L.), the number of times one strand links through the closed circle formed by the other strand (for reviews, see Wang 1980; Benham 1985). L. is an invariant integer for a permanently closed DNA duplex and the family of molecules differing

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Mike Scherfner,Torsten Vollandmeter which describes this constraint is the linking number (L.), the number of times one strand links through the closed circle formed by the other strand (for reviews, see Wang 1980; Benham 1985). L. is an invariant integer for a permanently closed DNA duplex and the family of molecules differing

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Mike Scherfner,Torsten Vollandc RNA subunit and a protein co-factor. The RNA subunit is able to recognize and cleave tRNA precursors (ptRNAs) at the correct site when the reaction is carried out in buffers that contain a high concentration of Mg. ions. This RNA, by itself, behaves as a true enzyme. When present in small amounts

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Mike Scherfner,Torsten Vollandhood cancer, retinoblastoma (Knudson 1971). Since then, the Rb gene product (pRb) has established itself as a protein of central importance to those researchers interested in the regulation of cellular proliferation and the mechanisms of cellular transformation. Its biological properties do, however

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Mike Scherfner,Torsten Volland there are several well-documented examples of regulatory proteins, such as the lambda repressor. The intimate molecular mechanism of the interaction between these prokaryotic regulatory proteins and the DNA double helix is known in great detail. However, it is not yet clear how this interaction mod