Titlebook: Mathematical Oncology 2013; Alberto d‘Onofrio,Alberto Gandolfi Book 2014 Springer Science+Business Media New York 2014 Anticancer therapy.

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A General Framework for Multiscale Modeling of Tumor–Immune System Interactionsmmune system on microscopic, mesoscopic, and macroscopic scales. The presented structures may be a basis for a description on the sub–cellular, cellular, and macroscopic levels. Important open problems are indicated.

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The Power of the Tumor Microenvironment: A Systemic Approach for a Systemic Diseasehe host including blood vessel formation, immune cell function, and nutrient recycling. This review summarizes a variety of time-dependent mathematical models that focus on the consequences of tumor growth within an evolving microenvironment, represented by a dynamic carrying capacity. Transcending

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Modeling Immune-Mediated Tumor Growth and Treatmentf cancers. In this chapter we develop mathematical models that describe the immune response to the presence of a tumor. We then use these models to explore a variety of immunotherapy treatments, both alone and in combination with other therapies.

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A Hybrid Multiscale Approach in Cancer Modelling and Treatment Predictionodels can help in studying cancer progression and serve as an in silico test base for comparing and optimizing various multi-modality anticancer treatment protocols. Here, we discuss one such hybrid multiscale approach, interlinking individual cell behavior with the macroscopic tissue scale. Using t

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