Titlebook: Mathematical Models for Therapeutic Approaches to Control Psoriasis; Priti Kumar Roy,Abhirup Datta Book 2019 The Author(s), under exclusiv

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Fractional Approach of the Formation of Psoriasis during Release of Cytokineshis feature that the subsequent phase of the model not only depends upon its present state but also upon all of its chronological situations (Elbasha et al, Nonlinear Anal: Real World Appl 12(5):2692–2705, 2011)[.].

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Regulating Growth of Keratinocytes through Feedback Mechanism with Delay Effect in Psoriatic System response of cytokines and decreases activation and proliferation of Keratinocytes. As a mathematical understanding of this chapter, we have tried to expose the activation of Keratinocyte cells due to T-Cells-mediated cytokines, that is the causal effect of excessive growth of Keratinocyte cell population.

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Inhibition of Excessive Keratinocyte Growth in Psoriasis using Drugs Cyclosporin and FK506. T-Cells and DCs. Another method to produce Keratinocytes is the interaction between T-Cells and Keratinocytes itself. We have also set the drug in that interaction to control the growth of Keratinocytes, whose surplus production generates the disease Psoriasis.

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Basic Mathematical Model on Immunopathogenic Plaque of Psoriasisological findings on the disease reveal that Helper T-Cells in the human blood as well as Dendritic Cells (DCs) play a significant role in inflicting the disease. Further, clinical research suggests that excessive generation of nitric oxide through a complex chain of biochemical events causes scalin