Titlebook: Mathematical Descriptors of Molecules and Biomolecules; Applications in Chem Subhash C. Basak Book 2025 The Editor(s) (if applicable) and T

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Ramanathan Natarajan,Subhash C. Basak,Claudiu N. Lungus and oxidative stress, protein misfolding and translational dysfunction, autophagy and microglia activation. This indicates that although the original cause may differ in individual diseases or even subtypes of certain disorders, these disrupted common cell functions and signaling, together with ag

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Suman K. Chakravartin, resulting in a broad range of neurological and non-neurological comorbidities. The concept of epileptic encephalopathies entails that the encephalopathy aspect of the overall condition is primarily driven by the epileptic activity of the disease, which often manifests as specific and pathological

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Arpita Poddar,Ranita Pal,Shanti Gopal Patra,Pratim Kumar Chattarajn deficiency, impaired effectiveness of insulin action, or both. The prevalence of Type 2 diabetes mellitus (T2DM) increases with age and dementia also increases its incidence in later life. Recent studies have revealed that T2DM is a risk factor for cognitive dysfunction or dementia, especially tho

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Denis Sabirov,Alexandra Zimina,Igor Shepelevich-onset alzheimer’s disease (LOAD) is the result of multiple susceptibility genes, each one contributing a small amount to the total risk. Smaller-scale genetic association studies identified the e4 allele of the apolipoprotein E (APOE) gene as the best established LOAD risk factor, increasing risk b

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Apurba K. Bhattacharjee-onset alzheimer’s disease (LOAD) is the result of multiple susceptibility genes, each one contributing a small amount to the total risk. Smaller-scale genetic association studies identified the e4 allele of the apolipoprotein E (APOE) gene as the best established LOAD risk factor, increasing risk b

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Hierarchy of Descriptors: From Topology to Bio-descriptors,are used to quantify salient aspects of molecular and biomolecular strucuraes. This chapter discusses the nature and methods of calculations of various classes of chemodescripotors and biodescriptors developed and used by reseaerchers during the past century.

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