Titlebook: Masters Theses in the Pure and Applied Sciences; Accepted by Colleges Wade H. Shafer Book 1989 Plenum Press, New York 1989 Natur.Systems En

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INTER

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Wade H. Shafery high reaction temperatures of this hetero variant of the well-known 3,3-sigmatropic reaction limited their applicability to selected molecules. Since about 1970, charge acceleration enabled a significant reduction of the reaction temperature to be achieved, and cation- and anion-promoted rearrange

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Acetaminophen

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Wade H. Shafermical advantages. The first successful total syntheses of natural products incorporating the aza-Claisen rearrangement as a key step emphasized the synthetic potential. To date the aza-Claisen rearrangements are far from being exhausted. Still, an enantioselectively catalyzed variant has to be devel

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