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Titlebook: Mass Spectrometry in the Biological Sciences: A Tutorial; Michael L. Gross Book 1992 Springer Science+Business Media Dordrecht 1992 Mass S

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書(shū)目名稱(chēng)Mass Spectrometry in the Biological Sciences: A Tutorial
編輯Michael L. Gross
視頻videohttp://file.papertrans.cn/626/625275/625275.mp4
叢書(shū)名稱(chēng)Nato Science Series C:
圖書(shū)封面Titlebook: Mass Spectrometry in the Biological Sciences: A Tutorial;  Michael L. Gross Book 1992 Springer Science+Business Media Dordrecht 1992 Mass S
描述The developments in mass spectrometry over the past fifteen years have been impressive in their implications in bioanalytical chemistry. The achievements begin with the inventions of Cf-252 Plasma Desorption Mass Spectrometry by Macfarlane and Fourier Transform Mass Spectrometry by Comisarow and Marshall in the mid 1970s. The former showed the feasibility of producing large gas-phase ions from large biomolecules whereas the latter enhanced the capabilities for ion trapping especially in analytical mass spectrometry. A major achievement was the development by Barber of Fast Atom Bombardment (FAB) mass spectrometry, an advance that heralded a new era in biological mass spectrometry. Contemporary and routine instruments such as magnetic sectors and quadrupoles were rapidly adapted to F AB, and nearly the entire universe of small molecules became amenable to study by mass spectrometry. The introduction of FAB also paved the way for improvement of instrument capability. For example, the upper mass limit of magnet sector mass spectrometers was increased by nearly an order of magnitude by the instrument manufacturers. Furthermore, the technique of tandem mass spectrometry (MS/MS) was give
出版日期Book 1992
關(guān)鍵詞Mass Spectrometry; Nucleotide; bacteria; biochemistry; cell membrane; chemistry; protein; proteins; supercri
版次1
doihttps://doi.org/10.1007/978-94-011-2618-2
isbn_softcover978-94-010-5157-6
isbn_ebook978-94-011-2618-2Series ISSN 1389-2185
issn_series 1389-2185
copyrightSpringer Science+Business Media Dordrecht 1992
The information of publication is updating

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Hybrid Tandem Mass Spectrometrystrated by MS/MS and MS/MS/MS analyses of peptides, xenobiotic metabolites and other compounds of biological importance.The versatility of operation (with respect to scan modes and the conditions utilized for collisionally activated decomposition) is a particular advantage of hybrid instruments.
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Laser Desorption Mass Spectrometry. Part I: Basic Mechanisms and Techniquessed. Emphasis is placed on results which elucidate energy transfer to the sample and ionization of molecules and their dependence on the laser parameters. Mass analysis by time-of-flight mass spectrometry is introduced.
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Continuous-Flow Fast Atom Bombardment Mass Spectrometry in Analytical Biochemistryresents some applications concerning the analysis of proteins and peptides. A description of the operational aspects of the technique is presented along with a discussion of the features and criteria of stable operation. Analytical advantages are presented by using problems encountered in protein ch
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Neutralization-Reionization Mass Spectrometry: Fundamental Studies and Analytical Applicationss are formed by charge exchange or dissociation of mass-selected ions and subsequently reionized for mass-analysis and detection. This method can be particularly useful for the characterization of ion structures, as shown here for C.H.O+ isomers. NRMS enables the study of highly reactive or marginal
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