Titlebook: Marburg- and Ebolaviruses; From Ecosystems to M Elke Mühlberger,Lisa L. Hensley,Jonathan S. Towner Book 2017 Springer International Publish

修飾語

Nonhuman Primate Models of Ebola Virus Diseasehat currently serve as gold standards for testing ebolavirus vaccines and therapeutic agents and elucidating underlying mechanisms of pathogenesis. Although multiple models have been explored over the past 50?years, the predominance of published work has been performed in macaque models. This chapter will focus on the most commonly used models.

maladorit

黃瓜

OVER

Therapeutics Against Filovirus Infectionct on the host, effective approaches to treat patients during infection will be identified. The ability to manage outbreaks with medical interventions beyond supportive care will require clinical trial design that will balance the benefits of the patient and scientific community.

BRACE

抗生素

Reverse Genetics of Filoviruses. Thus, reverse genetics systems represent powerful research tools. Here we provide an overview of available reverse genetics systems for the generation of recombinant filoviruses, potential applications, and the achievements that have been made using these systems.

使入迷

彩色的蠟筆

Ecology of Filovirusesness and over 13,200 reported deaths. Since their discovery, researchers from many scientific disciplines have worked to better understand the natural history of these deadly viruses. Citing original research wherever possible, this chapter reviews laboratory and field-based studies on filovirus eco

CRUDE

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Clinical Management of Ebola Virus Disease Patients in Low-Resource Settingsitically ill that are available in better resourced settings, such as advanced therapeutic interventions and abundant staff. In addition to these limitations may be added those imposed by the remote tropical locations, where EVD outbreaks occur. In this setting, a safe environment is created where h