Titlebook: Management of Soft Tissue Sarcoma; Murray F. Brennan,Cristina R. Antonescu,Robert G. Book 2016Latest edition Springer International Publi

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Murray F. Brennan MD,Cristina R. Antonescu MD,Kaled M. Alektiar MD,Robert G. Maki MD, PhD

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Murray F. Brennan MD,Cristina R. Antonescu MD,Kaled M. Alektiar MD,Robert G. Maki MD, PhD

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pecific recommendations on chemotherapy as a function of speManagement of Soft Tissue Sarcoma, 2nd Edition provides the most comprehensive analysis of demographics and natural history currently available for ?these lesions, based on the authors’ experience with over 10,000 patients. Sections regardi

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Book 2016Latest editionhese lesions, based on the authors’ experience with over 10,000 patients. Sections regarding radiation therapy not found in the previous text have been expanded, as have updates on molecular characteristics of sarcomas and chemotherapy studies published since the prior edition. Clinical and molecula

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General Description the term soft tissue sarcoma to differentiate it from carcinoma [3]. The first classification of sarcoma has been attributed to Abernethy in 1804. Johannes Müller (1801–1858) has been credited with coining the term desmoid in 1838 [3]. Stout (1885–1967) published a seminal monograph in 1932 on the pathology and treatment of sarcomas [4].

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Liposarcomaound cell (high-grade) liposarcoma. The least common is (high-grade) pleomorphic liposarcoma. Each subtype has a very distinctive morphology, natural history, and genetic changes utilized in diagnosis.

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Epithelioid Sarcoma a slowly growing lesion, that metastasizes relatively early to lymph nodes, which will be positive in 1/3 to 1/2 of cases (Fig. 14.3) [2, 3]. The proximal type is often associated with a more aggressive clinical behavior, with local, regional, and metastatic disease developing over several years.

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