Titlebook: Management of Prostate Cancer; Eric A. Klein,J. Stephen Jones Book 2013Latest edition Springer Science+Business Media, LLC 2013 Brachyther

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Twenty Years and Counting: Is PSA Still Useful in 2010?, have been identified. Another issue in question is the value of PSA screening and the overdiagnosis of potentially indolent cancer. Recently, the effect of PSA screening on prostate cancer mortality has been evaluated in two large prospective randomized trials, which will be discussed in detail. Th

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Molecular Progression of Prostate Cancer: Androgens and Estrogens,vation, coactivator modification, as well as the intratumoral production of androgens. Meanwhile, the impact of estrogens and the estrogen receptor in prostate cancer development and treatment continues to be defined. Here, we review current concepts regarding the role of the sex-steroid hormone axi

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Prostate Cancer Risk Reduction by Chemoprevention,e in a higher risk group of men with a negative baseline biopsy found a 22.8 % relative risk reduction in prostate cancer (19.9 % vs. 25.1 %) with no increase in high grade prostate cancer. With respect to nutrient use, the Selenium and Vitamin E Cancer Prevention Trial found no favorable effect of

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Focal Therapy: Prostate Hemiablation as the First Historical Treatment Model for Focal Therapy of Eerstanding of tumor biology of early stage disease and promising outcomes of the first single- and two-institution trials, a fundamental background for hemi-ablation of early stage PCa has been created. While the preoperative identification of a unifocal lesion or unilateral cancer remains challengi

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Radiation Therapy in the Management of Locally Advanced Prostate Cancer,een when adding radiation therapy to ADT. The optimal duration of ADT in combination with radiation therapy for locally advanced prostate cancer is still subject to debate but the evidence points to an advantage to long-term ADT (≥2 years and 4 months) for the highest risk prostate cancer patients.

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