Titlebook: Management of Breast Cancer in Older Women; Malcolm Reed,Riccardo A. Audisio Book 2019Latest edition Springer Nature Switzerland AG 2019 T

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Mammographic Breast Screening in Older Women,ates over the past 30?years. Screening was implemented based on a number of randomised and non-randomised trials, which published promising results in the 1980s, suggesting a reduction in disease stage at diagnosis and a consequent survival benefit. Most of the early trials included women up to the

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Clinical Assessment: Comprehensive Geriatric Assessment,ng an “older” adult. Chronological age itself is less important than biological events in driving the aging process within an individual. However, the use of chronological age is a practical way of defining a target population. In geriatric oncology, 70?years is the most commonly used cutoff for def

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Multi-disciplinary Geriatric Oncology Clinics,en with breast cancer may not receive optimal therapy. We present evidence to support the use of comprehensive geriatric assessment of frail patients with breast cancer, to ensure optimisation of co-morbidity management and to facilitate optimal cancer therapy. Assessment should include evaluation o

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Primary Endocrine Therapy, a strategy adopted to varying degrees by different countries. It is a good option for the very frail or unfit older women with ER positive breast cancer. Selection for its use must take into account the probable life expectancy of the woman because secondary antioestrogen resistance develops after

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Adjuvant Endocrine Therapy,setting. Current guidelines recommend that patients with hormone receptor-positive disease be offered adjuvant endocrine therapy (ET). Oestrogen receptor (ER)-positivity progressively increases with age, with more than 80% of BCs being ER-positive in patients aged 65 and older. As such, given that t

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Adjuvant Systemic Therapy,cerns about patient fitness make decision-making for early-stage breast cancer particularly challenging in the context of a lack of age-specific evidence. As a result, older breast cancer patients are offered adjuvant systemic therapy less frequently..However, the use of adjuvant chemotherapy is sup