Titlebook: Magnetic Resonance in Experimental and Clinical Oncology; Proceedings of the 2 Jeffrey L. Evelhoch,William Negendank,Laurence H. Conferenc

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RLS898

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31P and 2H MRS Studies of Flavone Acetic Acid and Analogues,haracteristics. FAA is broadly active against murine transplantable solid tumors growing subcutaneously (s.c.) including several which are insensitive to standard chemo-therapeutic agents (1–5; see Table 1). Conversely, FAA has no activity against murine leukemias or lymphomas generally sensitive to

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Use of 1H MRS of Plasma and Tissue in Cancer Detection and Management,d. This article suggested that .H NMR of plasma could be used to detect the presence of cancer. Although never stated as such, the inference was that this test could be used to screen an asymptomatic population for cancer. Since we were already applying .H NMR in cancer detection and management we d

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Quantification of ,P NMR , Spectra,ility. To validate and extend these early results, spectra must be produced from well-defined locations which can be accurately mapped to anatomical features. These specta need to be quantified reproducibly and accurately. Local sensitivity factors are also required so that absolute concentrations c

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31P NMR Studies of Superficial Murine and Human Tumors,s after growth, radiation, hyperthermia, chemotherapy, hypoxia, and hyperglycemia have been demonstrated (1–5). In this paper we present some of our recent studies using .P NMR to study the effects of hyperglycemia in a murine fibrosarcoma. Hyperglycemia has been shown to cause thermal sensitization

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Integrated Magnetic Resonance Imaging and 31P-Magnetic Resonance Spectroscopy of Soft Tissue Massesship to surrounding organs, muscle compartments, fascial planes, bone and neurovascular structures. The signal intensity on MRI depends on the biophysical properties of tissues such as proton density and the intrinsic relaxation times of the protons being imaged (T. and T. values). Variations in the