Titlebook: Macromolecular Protein Complexes II: Structure and Function; J. Robin Harris,Jon Marles-Wright Book 2019 Springer Nature Switzerland AG 20

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Frataxin Structure and Function, Friedreich’s Ataxia. Valuable knowledge has been gained on the structural dynamics of frataxin, metal-ion-protein interactions, as well as on the effect of mutations on protein conformation, stability and internal motions. Additionally, laborious studies concerning the enzymatic reactions involved

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Structure and Function of the TREX-2 Complex, bind, facilitating integration of this phase of the gene expression pathway, as well as mediating the re-positioning of highly regulated actively transcribing genes (such as .) to nuclear pores (NPCs) to accelerate their activation. In . the TREX-2 complex is based on a Sac3 scaffold to which Thp1,

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The Anaphase Promoting Complex/Cyclosome (APC/C): A Versatile E3 Ubiquitin Ligase, as the emerging evidence of important APC/C roles in cellular processes beyond cell division control such as regulation of genomic integrity and cell differentiation of the nervous system. We consider the potential incipient role of APC/C dysregulation in the pathophysiology of the neurological dis

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TRiC/CCT Chaperonin: Structure and Function,iC plays an essential role in maintaining protein homeostasis, and dysfunction of TRiC is closely related to human diseases including cancer and neurodegenerative diseases. TRiC consists of eight paralogous subunits, each of which?plays a specific role in the assembly, allosteric cooperativity, and

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Mayara M. Miyachiro,Carlos Contreras-Martel,Andréa Dessen Deleuze and Guattari, Braidotti, Vint, and Wolfe), this proposed chapter examines how two recent Science Fiction texts present posthuman-animal figures within imaginative future worlds in ecocrisis. Both Paolo Bacigalupi’s . and Lawrence M. Schoen’s . present posthuman future scenarios that include