Titlebook: MHC Molecules: Expression, Assembly and Function; Robert G. Urban,Roman M. Chicz Book 1996 R.G. Landes Company and Chapman & Hall 1996 T c

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Major Histocompatibility Antigens: An Introduction,th of discovery on MHC molecules and antigen presentation in general, yet more and more detail continues to be uncovered. This chapter is intended to review some of the hallmark observations made in the last five years and to prepare those newly interested in immunology for the more detailed chapter

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The Major Histocompatibility Complex Genes and their Transcriptional Regulation,cuss the domain structure of class I and class II polypeptides and how this relates to the intron/exon structures of the genes. The bulk of the attention will be focused on the transcriptional regulatory mechanisms of class I and class II MHC genes. Our intention is not to provide an encyclopedic co

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Crystallographic Analysis of Peptide Binding by Class I and Class II Major Histocompatibility Antigmulate T cells. was interpreted to mean that histocompatibility molecules present small peptides to T cells.. Additional snapshots now seek to understand how these molecules bind diverse sets of peptides with nanomolar dissociation constants and half-lives measured in days.

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Epitope Prediction Algorithms for Class I MHC Molecules,es have demonstrated that many of these differences are directed toward the peptide-binding groove, where they help determine the specificity of peptide binding.. Each class I molecule has a preference for peptides with a characteristic length and amino acid sequence. The exact length requirements d

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