Titlebook: Lymphocyte Immunization Therapy (LIT) in Reproductive Failures; New Horizons Mohan Raut,Mugdha Raut Book 2022 Springer Nature Singapore Pte

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Recent Meta-Analyses and LITe study with maximum weightage in the Cochrane reviews (REMIS study) had methodological flaws, indicating that the results of the REMIS trial were incorrect. A new meta-analysis of studies incorporated in the Cochrane review omitting REMIS study showed better results in favor of LIT. Newer meta-anal

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Review of International Studies of LITequent Cochrane reviews showed no benefit of LIT. However, there were many studies published afterward that showed significant benefits of LIT in RPL/RIF. In this chapter, a review is done of all the studies that were published in the last 20 years (Post-REMIS studies). This chapter also includes a

Factual

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Future of LIT efficacy and safety of LIT. It holds great potential in the treatment of patients with reproductive failures, who have not responded to other modalities of treatment. It is essential to study the changes induced by LIT at the molecular level. It is important to identify the subgroups that will be b

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ARM

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Statistical Aspects of the Estimation of Human Risksill comment on the limitations in their ability to provide precise quantitative low-dose risk estimates. These constraints include: the existence of thresholds; incorporation of background, or spontaneous responses; and modification of the dose response by pharmacokinetic processes.

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Fault Detectability Index for Optimal Monitoring System Designy to avoid the inclusion of sensors other than those installed for control purposes. It can be done through a good definition of the functional cost. The capacity of this methodology is demonstrated with a set of typical critical faults that could occur to this complex process.

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