Titlebook: Lymphocyte Activation and Immune Regulation IX; Homeostasis and Lymp Sudhir Gupta,Eugene Butcher,William Paul Book 2002 The Editor(s) (if a

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T Cell Proliferation, Differentiation, and Restoration in Lymphopenic Individualsene-1 (RAG.) or sublethally irradiated normal mice, the transferred T cells proliferate, a phenomenon referred to as homeostasis-driven or lymphopenia-induced proliferation. Although deliberate antigen stimulation is not required, homeostatic T cell proliferation requires i) the engagement of T cell

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Migration of Primary and Memory Cd8 T Cellsfic adaptive immune response comprised of CD4 and CD8 T cells and B cells. Thus, there are multiple cellular players in the induction of the response and although our knowledge has increased dramatically in recent years, there is much to learn regarding the complex interplay of the various cell type

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https://doi.org/10.1007/978-1-4615-0757-4Antigen; Chemokine; Thymus; protein; proteins; virus

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Some Properties of T Cells in Animalsncerns the fact that T cells divide in the apparent absence of antigen when transferred to T cell deficient mice. The second investigates the finding that memory T cells contain very large amounts of mRNA for certain chemokines. These two phenomena will be discussed in separate sections below.

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Generation and Characterization of Memory Cd4 T Cellstcome of the immune challenge. However, the activated T cells are relatively short lived and little is known about the factors that determine the proportion that develop into long-lived memory cells. Furthermore, the behavior of memory cells upon re-encounter with antigen is poorly understood.

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