Titlebook: Locoregional Radionuclide Cancer Therapy; Clinical and Scienti Franklin C.L. Wong Book 2021 Springer Nature Switzerland AG 2021 locoregiona

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Human Cancer: Epidemiology, Hallmarks, and Defense Strategies, affect humans across spectrums of age, gender, or ethnicity. With the advent of modern medicine in the twenty-first century, the understanding of the pathophysiology of cancers and their relationship with human hosts can be summarized in hallmarks of cancer biology. Such understanding provides inva

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Cancer Treatment Modalities Systemic and Locoregional Approaches: Challenges and Opportunities of Mtherapies are essential for curative-intent treatments, and surgical resection remains the most common method to control localized cancers. Radiation therapy also has a vital role (with or without concurrent chemotherapy) for locoregional control. In addition, image-guided procedures such as emboliz

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Cancer Radiotherapy: General Considerations and Human Radiobiology,indicated as part of their comprehensive treatment plan. Here we provide an overview of the biologic mechanisms underlying radiation therapy, before examining the various radiotherapy modalities currently available in clinical practice, including modern innovations such as stereotactic ablative tech

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Radiation Dosimetry Considerations of Locoregional Radionuclide Cancer Therapy,ate and compare candidate radiopharmaceuticals, models that encompass the range of expected activity distributions in the tumor were examined to estimate the radiation-absorbed doses to tumor and to the tissues surrounding the tumor as a function of depth. These models were executed for the clinical

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Locoregional Unsealed Radionuclide Cancer Therapy: Experimental Findings,esigned and optimized. This chapter describes the experiences of locoregional radionuclide cancer therapy using small animal models of mice and rats as well as large animal models of dogs to examine the advantages and disadvantages of these tumor models. Comparison of tumor growth curves allows the

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