Titlebook: Liquid Biopsy in Cancer Patients; The Hand Lens for Tu Antonio Russo,Antonio Giordano,Christian Rolfo Book 2017 Springer International Publ

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神圣在玷污

Cancer Clonal Evolution and Intra-tumor Heterogeneity,romotes and drives a genetic selection mechanism of fittest cell clones. Usually, the origin of tumor heterogeneity may be explained by two theoretical models potentially complementary, the clonal evolution model and cancer stem cell (CSC) hypothesis. The intra-tumor heterogeneity detected in most o

ABHOR

Actionable Molecular Targets in Cancer Liquid Biopsy,technologies as well as in pathway-driven biology knowledge of the cancer process now allow medical science to adopt universal pre-analytical and analytic methodologies. The key aspect that currently concerns the medical oncology field still remains what molecular targets should be pursued in the cl

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Tartar

Liquid Biopsy in Non-Small Cell Lung Cancer (NSCLC),s back, new advances and discoveries make them, together with the ctDNA, a very promising tool. In the following chapter we will discuss the recent advances of liquid biopsy in NSCLC highlighting the possible clinical utility of CTCs, ctDNA and exosomes.

潰爛

Liquid Biopsy in Esophageal, Gastric, and Pancreatic Cancers, pancreatic cancers for a better desease management. In this chapter we will discuss how CTCs, exosomes and circulating nucleic acids can be used to obtain prognostic and predictive information and also could be a useful tool for early diagnosis.

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FLACK

Liquid Biopsies in Malignant Melanoma: From Bench to Bedside,ecting the right treatment for the proper patient..In this new scenario, serological tumour markers should be reviewed. Among them, potential circulating biomarkers such as cell-free DNA, exosomes, microRNA and circulating tumour cells have been identified..In this chapter, we will summarize classic

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Clinical Practice Implications: Monitoring Drug Response and Resistance, involve solid tissues but the extraction of blood or other body fluids [3]. Liquid biopsy cannot completely replace the tissue biopsies, but it may offer a valid alternative for patients with advanced disease who have no tissue availability or to refine the oncological decision-making process [1–3]