Titlebook: Lipids in Health and Disease; Peter J. Quinn,Xiaoyuan Wang Book 2008 Springer Science+Business Media B.V. 2008 Activation.Lipid.Metabolism

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0306-0225 m is regulated in the liver and how fatty acids are desaturated are subjects considered in the first part of this volume. This section also deals with the modulation of protein function and inflammation by unsa978-90-481-8001-1978-1-4020-8831-5Series ISSN 0306-0225 Series E-ISSN 2542-8810

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Modulation of Inflammatory Cytokines by Omega-3 Fatty Acids of nuclear transcription factors, such as NFκB, and reduce the production of pro-inflammatory enzymes and cytokines, including COX-2, tumor necrosis factor (TNF)-α, and interleukin (IL)-1β. This chapter focuses on the evidence from recent studies using new experimental models.

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Lipids in the Assembly of Membrane Proteins and Organization of Protein Supercomplexes: Implicationsnted that changes in phosphatidylethanolamine levels results in misfolding and topological misorientation of membrane proteins leading to dysfunctional proteins. Examples are presented for diseases in which proper protein folding or topological organization is not attained due to either demonstrated

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Altered Lipid Metabolism in Brain Injury and Disordersr outcome in many brain pathologies. Apolipoprotein E is the principal cholesterol carrier protein in the brain, and the gene encoding the variant Apolipoprotein E4 is a significant risk factor for Alzheimer’s disease. Parkinson’s disease is to some degree caused by lipid peroxidation due to phospho

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The Role of Phospholipid Oxidation Products in Inflammatory and Autoimmune Diseasesstress, including lung, skin, and eyes, increased levels of OxPL are suggested to contribute to inflammatory conditions. Moreover, accumulation of OxPL causes general immunmodulation and may lead to autoimmune diseases. Evidence is accumulating that OxPL play a role in lupus erythematosus, antiphosp

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