Titlebook: Lipid Metabolism in the Healthy and Disease Heart; Ger J. Vusse,Hans Stam Book 1992 Springer Science+Business Media Dordrecht 1992 ATP.Lip

STYX

Jos M. J. Lamers,Dick H. W. Dekkers,Karel Bezstarosti,Johanna T. A. Meij,Han A. A. van Heugten

debacle

HEW

Paradoxical role of lipid metabolism in heart function and dysfunction,ciated with cardiac dysfunction and cell damage in both ischemic and diabetic hearts. Alterations in the composition of membrane phospholipids are also consiered to change the activities of various membrane bound enzymes and subsequently heart function under different pathophysiological conditions.

有助于

四溢

The substrate specificity of phosphoinositide- phospholipase C in rat heart sarcolemma,very low rate (0.36 ± 0.08 nmol mg. min.). Unlike PtdIns(4,5)P., PLC-dependent PtdIns4P and Ptdlns hydrolysis was not inhibited by Ca. concentrations over 1 mM. The possibility of distinct isozymes being responsible for the different hydrolytic activities is discussed. (Mol Cell Biochem .: 27–31, 19

Cholagogue

LINES

Myocardial cell vulnerability to exogenous phospholipase attack,difference was much more pronounced in the latter. Finally, the cellular contents of ATP were maintained both in TG-loaded and hypothermic rewarmed myocytes, while energy depleted myocytes contained only about 25% of the normal ATP level. These results demonstrate that attack from exogenously added

注意

Phosphatidylcholine metabolism in ischemic and hypoxic hearts,emonstrate the possible rate-limiting role of choline kinase and reconfirm the regulatory role of the cytidylyltrans-ferase in the biosynthesis of phosphatidylcholine. (Mol Cell Biochem 116: 53–58, 1992)

CLEFT

Occurrence and Functions of the Phosphatidylinositol Cycle in the Myocardium,5) source other than PtdIns(4,5)P. contributing to the stimulated DAG, 6) role of the Ptdlns pathway in cardiomyocyte growth and gene expression during the hypertrophic response. (Mol Cell Biochem .: 59–67, 1992)

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