Titlebook: Leishmania and Leishmaniasis; Awanish Kumar Book 2013 Springer Science+Business Media New York 2013 Leishmania.Parasites.Tropical diseases

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Introduction,a second most prevalent parasitic disease. Leishmaniasis has been considered a tropical affliction that constitutes one of the six entities on the list of most important diseases of World Health Organization/Tropical Disease Research (WHO/TDR) viz. Malaria, Schistosomiasis, Filariasis, Chagas diseas

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Drugs and Diagnosis for Leishmaniasis,ble as branded products, meglumine antimoniate (Glucantime) and sodium stiboguconate (Pentostam) (Fig. 4.1) and in the generic form, Sodium Antimony Gluconate (Albert David Ltd., Kolkata). The drugs are given by i.v. and i.m. routes and their efficacies are equivalent at similar doses (Sundar and Ch

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Vaccines Against Leishmaniasis,DNA antigens have been identified as potential vaccine candidates in experimental animals but none have so far been approved for human use. To date there is no vaccine available against VL in routine use anywhere in the world. However, there is consensus that in the long term, vaccines ought to beco

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Antimonials and Resistance,mammal than trivalent [Sb(III)] salts. By the end of 1940s pharmaceutical research produced the current drug in use; the closely related organic pentavalent antimonial compounds Sodium antimony Gluconate (SAG) and Meglumine antimonite.