Titlebook: CURED I - LENT Late Effects of Cancer Treatment on Normal Tissues; Philip Rubin (Professor Emeritus, Chair Emeritus), Book 2008 Springer-V

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Moyed Miften PhD,Olivier Gayou PhD,David S. Parda MD,Robert Prosnitz MD,Lawrence B. Marks MDfor the L Group histiocytoses, which include Langerhans cell histiocytosis (LCH), Erdheim-Chester disease (ECD), and indeterminate cell histiocytosis (ICH). Although the phenotype of LCH histiocytes is distinct from that of ECD histiocytes and the clinical presentations of the pure forms of each dis

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Philip Rubin MD of clinical, imaging, and pathology findings, two patterns of CNS-LCH have been identified: granulomatous (“tumorous”) and non-granulomatous “neurodegenerative” (ND)-CNS-LCH. Granulomatous CNS-LCH can manifest with polyuria and polydipsia, seizures, increased intracranial pressure, or other signs,

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Noreen M. Aziz MD, PhD, MPhneed to screen novel compounds for their potential therapeutic effects, and once these have been "discovered" to understand their molecular actions, as the basis of using such compounds safely and for rational drug design. Pharmacology now uses all of the sophisticated molecular research techniques

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Radiation (and Medical) Biosurveillance,ealth-related quality of life. Progress by the (Children’s Oncology Group (COG) can be modeled or adapted for a adult malignancy, and is described in this report. Investigators from COG developed risk-based, exposure-related guidelines to provide recommendations for screening and management of late

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Medical Countermeasures to Radiation Injury,n, and treatment of radiation damage to normal tissue as a consequence of exposure of healthy populations, as well as from cancer treatment. The recent threat of radiological and nuclear terrorism as a consequence of a radiological dispersion device (RDD) or improvised nuclear device (IND) has raise

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The Role of Imaging in the Study of Radiation-Induced Normal Tissue Injury,es. One of the major challenges in the study of radiation (RT)-induced normal tissue injury is determining the appropriate endpoint. Patients’ symptoms have obvious clinical relevance; however, the scoring of symptoms is relatively subjective. Conversely, radiologic endpoints are potentially quantif