Titlebook: Ketamine for Treatment-Resistant Depression; The First Decade of Sanjay J. Mathew,Carlos A. Zarate, Jr. Book 2016 The Editor(s) (if applic

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Ketamine: Clinical Studies in Treatment-Resistant Depressive Disorders,ed. The main drawback of ketamine is that its antidepressant effects generally do not last more than one week. Several studies have, however, shown that repeated administration can maintain and prolong the response. Finally, clinical experience using repeated administration of ketamine has thus far

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,Ketamine’s Mechanisms of Rapid Antidepressant Activity: Evidence from Preclinical Studies,lucidate the drug’s mechanisms of antidepressant activity, with the majority of recent studies suggesting that increased levels of regional alpha-amino-3-hydroxy-5-methyl-4-isoxazole proprionic acid (AMPA) receptor activation and brain-derived neurotrophic factor (BDNF) expression, as well as enhanc

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Ketamine and Electroconvulsive Therapy,er doses—a longer time to post-procedure recovery. At present, the evidence does not support the routine use of ketamine for ECT, but ketamine may be useful for patients who require a rapid antidepressant response. The potential of combined ECT-ketamine treatment to increase efficacy in patients ref

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Janusz K. Rybakowski MD, PhD,Agnieszka Permoda-Osip,Alicja Bartkowska-Sniatkowskability, discrete and continuous distributions, moment generating functions, fundamental probability inequalities, the central limit theorem, and joint and conditional distributions of discrete and continuous random variab978-1-4614-2581-6978-1-4419-5780-1Series ISSN 1431-875X Series E-ISSN 2197-4136

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Gretchen Hermes MD, PhD,Gerard Sanacora MD, PhDbility, discrete and continuous distributions, moment generating functions, fundamental probability inequalities, the central limit theorem, and joint and conditional distributions of discrete and continuous random variab978-1-4614-2581-6978-1-4419-5780-1Series ISSN 1431-875X Series E-ISSN 2197-4136

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Carolyn Ines Rodriguez MD, PhD,Elias Dakwar MDbility, discrete and continuous distributions, moment generating functions, fundamental probability inequalities, the central limit theorem, and joint and conditional distributions of discrete and continuous random variab978-1-4614-2581-6978-1-4419-5780-1Series ISSN 1431-875X Series E-ISSN 2197-4136