Titlebook: Ketamine; From Abused Drug to Kenji Hashimoto,Soichiro Ide,Kazutaka Ikeda Book 2020 Springer Nature Singapore Pte Ltd. 2020 Ketamine.Antid

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Behavioral Pharmacology of Ketamine: An Overview of Preclinical Studies,e response and impairment of latent inhibition have been reported. However, relatively high doses seem to be necessary to yield these effects. Several lines of preclinical evidence have also shown the reinforcing and rewarding properties of ketamine, which are relevant to the abuse liability. To ove

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The Role of Gut Microbiota in the Antidepressant Effects of Ketamine,pathway. Additionally, there is growing evidence that the gut microbiota may play a crucial role in the antidepressant effects of ketamine. In this chapter, we will discuss recent findings regarding the correlation between gut microbiota and the antidepressant effects of ketamine and their potential

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Distinct Roles of NMDA Receptor GluN2 Subunits in the Effects of Ketamine and Its Enantiomers,/GluN3A, B subunits. The involvement of each NMDA receptor subunit in the neural mechanisms that underlie the various effects of ketamine remains unclear. This chapter focuses on GluN2 subunits and discusses the involvement of each GluN2 subunit in various pharmacological actions of ketamine.

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Effects of Ketamine on Pain and Depression Comorbidity,e also present some current therapies based on an understanding of the neurobiological changes that occur in pain and depression comorbidities, as well as ketamine as a promising approach in the treatment of pain and depression comorbidities.

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