Titlebook: Jaagsiekte Sheep Retrovirus and Lung Cancer; Hung Fan Book 2003 The Editor(s) (if applicable) and The Author(s), under exclusive license t

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Book 2003e pulmonary adenocarcinoma. The disease was first documented in South Africa in the 1800s, it has a wide geographical distribution, and it is of economic importance in high endemic regions. However, until very recently the nature of the etiologic agent was unclear, and relatively few laboratories actively studied the disease.

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0070-217X s of economic importance in high endemic regions. However, until very recently the nature of the etiologic agent was unclear, and relatively few laboratories actively studied the disease.978-3-642-62897-9978-3-642-55638-8Series ISSN 0070-217X Series E-ISSN 2196-9965

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A History of Ovine Pulmonary Adenocarcinoma (Jaagsiekte) and Experiments Leading to the Deduction orom previously infected sheep lungs. The optimal purification involved the concentration of lung lavage of freshly slaughtered sheep, an extraction with organic solvent, and final purification by both rate zonal and isopycnic centrifugation. Monoclonal and polyclonal antibodies were made against the

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