| 書目名稱 | Issues and Reviews in Teratology | | 副標(biāo)題 | Volume 3 | | 編輯 | Harold Kalter | | 視頻video | http://file.papertrans.cn/476/475843/475843.mp4 | | 圖書封面 |  | | 描述 | There is still no clear understanding of what causes the great majority of human congenital malformations. And since in most sorts of human disease and pathology that yet prevail prevention usually awaits understanding of cause, it is generally thought that the same is true of developmental aberrations. But is this true? For the relatively few congenital malformations whose causes are primarily environmental, it is plain that their discovery has enabled prevention, but not nec- essarily immediately. It took a generation from the time of the discovery that maternal rubella was teratogenic to learn how to immunize against it. Much debate occurred before it was appreciated that thalidomide was a teratogen, and only its removal from the pharmacist‘s shelf and the end of the epidemic of limb defects attributed to the drug overcame the last doubts. For other proven environmental teratogens doubts and difficulties still con- tinue. The claimed prevalence of fetal genital distortions due to female sex hor- mones may have been exaggerated. Some potentially teratogenic therapeutic drugs, like anticoagulants, anticonvulsants, and anticancer chemicals, are still pre- scribed despite this dange | | 出版日期 | Book 1985 | | 關(guān)鍵詞 | CNS; Chromosom; behavior; biology; cell; cell culture; chromosome; environment; genetics; nutrition; pathology | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4613-2495-9 | | isbn_softcover | 978-1-4612-9510-5 | | isbn_ebook | 978-1-4613-2495-9 | | copyright | Plenum Press, New York 1985 |
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