Titlebook: Is Capitalism Still Progressive?; A Historical Approac Cosimo Perrotta Book 2020 The Editor(s) (if applicable) and The Author(s), under exc

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Cosimo Perrottainite proliferative potential in vitro (for review, see K. 1996). This process, termed growth transformation or immortalization, is supposed to be a prerequisite for the virus’ ability to establish life-long persistent infection in humans. Since similar signal pathways are activated and similar gene

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Cosimo Perrotta establish EBV-positive epithelial cell lines from EBV-infected gastric carcinoma tissues and to characterize the cell lines and EBV infection in the cells. EBV, a ubiquitous human herpesvirus with oncogenic potential, is predominantly associated with the infection of two target tissues in vivo: (1)

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Cosimo Perrottancreasing number of human diseases. Generally considered the first human oncogenic virus because of a number of studies linking it with Burkitt‘s lymphoma and nasopharyngeal carcinoma (NPC), as well as its documented oncogenicity in nonhuman primates, EBVhas served as a model for identifying subsequ

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Cosimo Perrottatency (1). The BZLF1 (Z) protein is capable of binding to AP-1 sites as well as some sites unrelated to AP-1 (referred to as ZRE’s), and appears to function as a transcriptional transactivator through binding to these responsive promoter elements (2–5). However, it appears that the function of Z as

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The second is “which other EB viral genes are activated as the result of ZEBRA expression?”.At least three variables have been identified which affect ZEBRA expression; these are genome rearrangements such as occur in defective virus, cell background, and the response to different inducing agents.