Titlebook: Ionotropic Glutamate Receptors in the CNS; Peter Jonas,Hannah Monyer Book 1999 Springer-Verlag Berlin Heidelberg 1999 Glutamate receptors.

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The Synaptic Protein Network Associated with Ionotropic Glutamate Receptorsules located at the C-terminal tails of the receptor subunits. Even though the ion-channel characteristics of N-methyl-D-aspartate receptors (NMDARs) and . amino — 3 — hydroxy — 5 — methyl — 4 — isoxazolepropionic acid receptors (AMPARs) are well characterized, much of their cell biology and cell ph

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Cellular and Subcellular Distribution of Glutamate Receptors 1997) and will be mentioned only briefly here. Glutamate receptors are found in nearly all neurons and in many types of glia in the central nervous system (CNS), as well as in many cells in the peripheral nervous system and in other structures. Each ionotropic glutamate receptor subunit shows a dis

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Instantaneous

一大群

FIG

Kainate Receptorspharmacological tools has hampered the detection of these receptors in neurons of the central nervous system (CNS) and the determination of their physiological role. Until the cloning of the subunits that make up the kainate receptors, the evidence of their existence as independent receptors in neur

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Molecular Determinants Controlling Functional Properties of AMPARs and NMDARs in the Mammalian CNStic glutamate receptors (GluRs) that mediate excitatory synaptic transmission in the mammalian central nervous system (CNS). Both AMPARs and NMDARs are multimeric proteins, probably tetramers, formed by a variety of molecularly distinct subunits. AMPARs can be assembled from four types of subunits,

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Morphological Characteristics of Glutamatergic Synapses in the Hippocampus nerve cells. It was much later on, after the introduction of electron microscopy to the study of nervous tissue, that this term was also applied to specialized membrane contacts visible in thin sections. The first reports on the fine structure of synaptic contacts between individual neurons and the

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Glutamate-Mediated Synaptic Excitation of Cortical Interneuronsons) have transregional axonal projections and release glutamate onto their postsynaptic target cells. In contrast, interneurons have local, but often extensive, axonal arborizations and use γ-aminobutyric acid (GABA) as a transmitter. Although interneurons represent only approximately 10% of the ne

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