Titlebook: Ion Channels and Transporters of Epithelia in Health and Disease; Kirk L. Hamilton,Daniel C Devor Book 2016 American Physiological Society

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Physiologic Influences of Transepithelial K+ Secretions through the apical membrane. Beyond excretion, transepithelial K. secretion serves to create the high K. concentration of endolymph in the inner ear that supports sensation of sound and body orientation. For several epithelia such as those in airways and gastric mucosa, the elevated K. concentrati

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Volume Regulation in Epitheliavolume regulation are cloned. The volume-regulated anion channel (VRAC) exhibiting specific electrophysiological characteristics seems exclusive to serve cell volume regulation. This is contrary to K. channels as well as cotransporters and exchange mechanisms that may serve both transepithelial tran

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Thiazide-Sensitive NaCl Cotransporteroning over two decades ago, much has been learned about the physiological transport properties of NCC, its regulation, and its connections to human disease. In this chapter, I provide an overview of the biology of this important cotransporter.

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