Titlebook: Ion Channels and Ion Pumps; Metabolic and Endocr Piero P. Foà (Professor Emeritus),Mary F. Walsh (A Book 1994 Springer-Verlag New York, Inc

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Endogenous Regulation of Sodium Pump Activity,ffort to identify a plasma-borne substance that was natriuretic by virtue of its ability to inhibit cellular sodium transport and which might increase vascular reactivity as a result of a similar action on vascular smooth muscle had not yet succeeded. Ten years later, in 1991, this effort appeared to have achieved its first major breakthrough.

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The Role of Potassium Ions in the Control of Heart Function,u potential is called phase 3. The final phase 4 continues to the next rapid depolarization. The action potential is the result of a concerted action of inward (depolarizing) and outward (hyperpolar-izing) ionic currents. The outward component is carried by K. ions through potassium-permeable transmembrane proteins, the potassium channels.

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Calcium Channels in Cells of the Anterior Pituitary,of phosphorylation and dephosphorylation of important intracellular proteins participate in the control of pituitary hormone secretion. The actions of these intracellular substances are intimately related to those of the central regulator of secretion, the calcium ion.

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[Ca2+]i and Contraction of Arterial Smooth Muscle,ntractile force of myosin light chain phosphorylation. I will also briefly discuss the mechanisms altering the dependence of myosin phosphorylation on [Ca.]. (ie, the [Ca.]. sensitivity of phosphorylation).

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Hormonal Modulation of Sodium Pump Activity: Identification of Second Messengers,bserves the secondary transport of other amino acids, sugars, calcium ions, and protons. In more general terms the sodium pump is the major mechanism responsible for the ability of the body to regulate levels of sodium and potassium. The energy spent in this capacity is a major source of heat production.