Titlebook: Invariant Natural Killer T-Cells; Methods and Protocol Chaohong Liu Book 2021 The Editor(s) (if applicable) and The Author(s), under exclus

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Identification of Rare Thymic NKT Cell Precursors by Multiparameter Flow Cytometry,ysis of NKT cells at the HSA. stage can shed light on defects in the maturation/differentiation of the different NKT cell subsets (NKT1, 2, and 17). Unlike HSA. NKT cell subsets, HSA. NKT cell precursors are not accurately identified by flow cytometry because of their extreme rarity. Here, we descri

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Book 2021horitative and practical, .Invariant Natural Killer T-Cells: Methods and Protocols. is an ideal guide for researchers working with and studying iNKT cells, perhaps to provide a deeper knowledge of the human immune system..

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1064-3745 expertsThis detailed book focuses on various aspects of Invariant Natural Killer T-Cells (iNKT), which are known to contribute to homeostasis and autoimmunity and can also cause various pathological responses such as allergy, infection, excessive autoimmune response, and cancer. The volume explores

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Book 2021y and can also cause various pathological responses such as allergy, infection, excessive autoimmune response, and cancer. The volume explores techniques for identification and isolation of iNKT cells, iNKT cell activation and transformation, as well as proliferation and differentiation and much mor

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Methods for Studying Mouse and Human Invariant Natural Killer T Cells,lood mononuclear cells or from human HSC cells engineered with iNKT TCR gene (denoted as hPBMC-iNKT cells or hHSC-iNKT cells, respectively), and (3) characterize mouse and human iNKT cells in vitro and in vivo.

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Detection of Mouse Type I NKT (iNKT) Cells by Flow Cytometry,sential role in the orchestration of the innate and adaptive immune responses against various diseases. Here, we will review the process of identifying mouse type I NKT cells by flow cytometry, which serves as a foundational technique for studying these cells.

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,Redirecting iNKT Cell Antitumor Immunity with α-GalCer/CD1d-scFv Fusion Proteins,hich is able to recruit iNKT cells to the tumor site and induce tumor regression. Importantly, recombinant CD1d fusion proteins loaded with α-GalCer demonstrated sustained activation of iNKT cells upon repeated injections and superior tumor control, as compared to α-GalCer treatment.