| 書(shū)目名稱 | Introduction to Synthetic Biology | | 副標(biāo)題 | About Modeling, Comp | | 編輯 | Mario Andrea Marchisio | | 視頻video | http://file.papertrans.cn/475/474258/474258.mp4 | | 概述 | Explains how to make mathematical models of synthetic gene circuits.Presents concepts such as kinetics, circuit dynamics and equilibria, stochastic and deterministic simulations, parameter analysis an | | 叢書(shū)名稱 | Learning Materials in Biosciences | | 圖書(shū)封面 |  | | 描述 | The?textbook?is based on the lectures of the course “Synthetic Biology” for Master’s students in biology and biotechnology at the Harbin Institute of Technology. The goal of the?textbook?is to explain how to make mathematical models of synthetic gene circuits that will, later on, drive the circuit implementation in the lab. Concepts such as kinetics, circuit dynamics and equilibria, stochastic and deterministic simulations, parameter analysis and optimization are presented. At the end of the?textbook, a chapter contains a description of structural motifs (e.g. positive and negative feedback loops, Boolean gates) that carry out specific functions and can be combined into larger networks. Moreover, several chapters show how to build up (an analyse, where possible) models for synthetic gene circuits with four different open-source software i.e. COPASI, XPPAUT, BioNetGeN, and Parts & Pools-ProMoT. | | 出版日期 | Textbook 2018 | | 關(guān)鍵詞 | Synthetic Biology; Mathematical Models; Synthetic Gene Circuits; Structural Motifs; Parameter Analysis; S | | 版次 | 1 | | doi | https://doi.org/10.1007/978-981-10-8752-3 | | isbn_softcover | 978-981-10-8751-6 | | isbn_ebook | 978-981-10-8752-3Series ISSN 2509-6125 Series E-ISSN 2509-6133 | | issn_series | 2509-6125 | | copyright | Springer Nature Singapore Pte Ltd. 2018 |
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