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Titlebook: Intrinsically Disordered Proteins; Vladimir N. Uversky Book 2014 The Author(s) 2014 Binding Promiscuity.Conformational Ensemble.Intrinsica

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發(fā)表于 2025-3-21 18:01:58 | 只看該作者 |倒序?yàn)g覽 |閱讀模式
書(shū)目名稱Intrinsically Disordered Proteins
編輯Vladimir N. Uversky
視頻videohttp://file.papertrans.cn/474/473268/473268.mp4
概述Discusses applications of IDPs and IDPRs as potential drug targets.Includes an introduction to the concept of protein intrinsic disorder.Provides an overview of current literature in the field.Include
叢書(shū)名稱SpringerBriefs in Molecular Science
圖書(shū)封面Titlebook: Intrinsically Disordered Proteins;  Vladimir N. Uversky Book 2014 The Author(s) 2014 Binding Promiscuity.Conformational Ensemble.Intrinsica
描述In this brief, Vladimir Uversky discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). Beginning with an introduction to the concept of protein intrinsic disorder, Uversky then goes on to describe the peculiar amino acid sequences of IDPs, their structural heterogeneity, typical functions and disorder-based binding modes. In the final sections, Uversky discusses IDPs in human diseases and as potential drug targets. This volume provides a snapshot to researchers entering the field as well as providing a current overview for more experienced scientists in related areas.
出版日期Book 2014
關(guān)鍵詞Binding Promiscuity; Conformational Ensemble; Intrinsically Disordered Protein; Protein Folding; Protein
版次1
doihttps://doi.org/10.1007/978-3-319-08921-8
isbn_softcover978-3-319-08920-1
isbn_ebook978-3-319-08921-8Series ISSN 2191-5407 Series E-ISSN 2191-5415
issn_series 2191-5407
copyrightThe Author(s) 2014
The information of publication is updating

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沙發(fā)
發(fā)表于 2025-3-22 00:18:42 | 只看該作者
Vladimir N. Uverskyeares Betriebsverhalten weisen Diodenbrücken mit Gl?ttungskondensatoren auf der Gleichspannungsseite auf. In diesem Fall wird der Verschiebungsfaktor cos . aufgrund des fehlenden Steuereingriffs (. = 0°) ungef?hr 1 sein. Der Leistungsfaktor A wird allerdings aufgrund der Strom—Harmonischen von 1 abw
板凳
發(fā)表于 2025-3-22 00:54:11 | 只看該作者
eares Betriebsverhalten weisen Diodenbrücken mit Gl?ttungskondensatoren auf der Gleichspannungsseite auf. In diesem Fall wird der Verschiebungsfaktor cos . aufgrund des fehlenden Steuereingriffs (. = 0°) ungef?hr 1 sein. Der Leistungsfaktor A wird allerdings aufgrund der Strom—Harmonischen von 1 abw
地板
發(fā)表于 2025-3-22 05:04:47 | 只看該作者
Intrinsically Disordered Proteins,the fall of one of the major paradigms in structural biology. Contrarily to the more than a century-old belief that the unique function of a protein is determined by its unique structure, which, in its turn, is defined by the unique amino acid sequence, many biologically active proteins lack stable
5#
發(fā)表于 2025-3-22 08:57:32 | 只看該作者
Vladimir N. UverskyDiscusses applications of IDPs and IDPRs as potential drug targets.Includes an introduction to the concept of protein intrinsic disorder.Provides an overview of current literature in the field.Include
6#
發(fā)表于 2025-3-22 16:13:23 | 只看該作者
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發(fā)表于 2025-3-22 18:36:40 | 只看該作者
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發(fā)表于 2025-3-22 23:40:12 | 只看該作者
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發(fā)表于 2025-3-23 01:22:57 | 只看該作者
Book 2014ordered domains and functional IDP regions (IDPRs). Beginning with an introduction to the concept of protein intrinsic disorder, Uversky then goes on to describe the peculiar amino acid sequences of IDPs, their structural heterogeneity, typical functions and disorder-based binding modes. In the fina
10#
發(fā)表于 2025-3-23 08:47:49 | 只看該作者
Book 2014l sections, Uversky discusses IDPs in human diseases and as potential drug targets. This volume provides a snapshot to researchers entering the field as well as providing a current overview for more experienced scientists in related areas.
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