Titlebook: Interrelations between Essential Metal Ions and Human Diseases; Astrid Sigel,Helmut Sigel,Roland K.O. Sigel Book 2013 Springer Science+Bus

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Visual-Acuity

Manganese in Health and Disease,cessive exposure or intake may lead to a condition known as manganism, a neurodegenerative disorder that causes dopaminergic neuronal death and parkinsonian-like symptoms. Hence, Mn has a paradoxal effect in animals, a Janus-faced metal. Extensive work has been carried out to understand Mn-induced n

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Iron: Effect of Overload and Deficiency,ential element in a wide range of biological phenomena, being critical for the function of an enormous array of enzymes, energy transduction mechanisms, and oxygen carriers. The redox nature of iron renders the metal toxic in excess and consequently all biological organisms carefully control iron le

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Cobalt: Its Role in Health and Disease,l roles of Cbl and the importance of cobalt in human health. Cbl acts as the cofactor for two enzymes, i.e., methylmalonyl-CoA mutase and methionine synthase, in humans. Both enzymes are important for health. In addition, unlike other water-soluble vitamins, there is a unique absorption, delivery, a

Entropion

characteristic

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Irremediable

Molybdenum in Human Health and Disease, a pterin-based molybdenum cofactor (Moco) in their active site. In these enzymes, molybdenum catalyzes oxygen transfer reactions from or to substrates using water as oxygen donor or acceptor. Molybdenum shuttles between two oxidation states, Mo. and Mo.. Following substrate reduction or oxidation,

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Silicon: The Health Benefits of a Metalloid,se as an additive in the food and beverage industry. As a result, humans come into contact with silicon through both environmental exposures but also as a dietary component. Moreover, many forms of silicon, that is, Si bound to oxygen, are water-soluble, absorbable, and potentially bioavailable to h

Arthropathy

Arsenic. Can This Toxic Metalloid Sustain Life?,high arsenate and low phosphate, is able to grow using arsenic instead of phosphorus. This claim, and subsequent studies to evaluate GFAJ-1, has brought new attention to the question of whether arsenic can play an essential or sustaining role for living organisms. If true, this would be in stark con