Titlebook: International Relations and Heritage; Patchwork in Times o Rodrigo Christofoletti,Maria Leonor Botelho Book 2021 The Editor(s) (if applicab

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Marie-Alix Molinié-Andlauerosed as novel early end point because the CRM status can account for effects on DFS and overall survival after chemoradiation, radiation (RT), or surgery alone. Consensus is needed to define the most appropriate end points in both early and phase III trials in locally advanced cancer.

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Jorge Elices Ocónweek course of preoperative chemotherapy. This cut-off was recently confirmed in a US study, where investigators did follow-up PET not 14?days but 6?weeks after initiation of chemotherapy. It was further noticed that the metabolic response to induction chemotherapy revealed as an independent prognos

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Manuel Burón non-intestinal-type tumors, this challenges the paradigm “no goblets no Barrett’s”. Moreover, even the cancer risk of intestinal-type metaplasia has seriously been questioned by a Danish population-based study where Barrett’s mucosa turned out to be only a weak indicator of esophageal and GEJ cance

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Karine Lima da Costaerative outcomes and similar oncologic results. However, the conversion rate of LTME is around 17?%. The literature supporting RTME is more limited. Robotic rectal resection appears to have similar postoperative and oncologic outcomes compared to LTME. RTME results in higher costs and possibly lower

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Vitória dos Santos Acerbioadjuvant therapy (50?%). The most frequently used instruments were the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (QLQ-C30), its colorectal cancer specific module QLQ-CR38, and the Medical Outcomes Study Short-Form 36 items questionnaire. Findin

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e response (pCR) rate was about 10?% higher in the delayed-surgery group. There were no differences in sphincter preservation and R0 resection rate between the two groups. Small studies suggest no differences in the oncological outcomes. Regarding elderly patients who were unfit for chemotherapy, sh

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Rodrigo Christofolettierative outcomes and similar oncologic results. However, the conversion rate of LTME is around 17?%. The literature supporting RTME is more limited. Robotic rectal resection appears to have similar postoperative and oncologic outcomes compared to LTME. RTME results in higher costs and possibly lower

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Bruno Miranda Zétolaoadjuvant therapy (50?%). The most frequently used instruments were the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (QLQ-C30), its colorectal cancer specific module QLQ-CR38, and the Medical Outcomes Study Short-Form 36 items questionnaire. Findin