Titlebook: Intensive Care Medicine; Annual Update 2009 Jean-Louis Vincent (Head) Conference proceedings 2009 Springer-Verlag New York 2009 Emergency M

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Endotoxin Tolerance: Mechanisms and Clinical Applicability of the most powerful microbial stimulants of immune and non-immune cells. The immune system responds to LPS with a systemic production of pro- and anti-inflammatory cytokines, such as tumor necrosis factor (TNF)-α, interleukin (IL)-6 and IL-10, primarily aimed to eliminate invading pathogens and su

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Anticlimax

Measurement of Carbon Monoxide: From Bench to Bedsideen reported to have cytoprotective and anti-oxidant activities [.]. In addition, other studies have suggested that endogenously generated carbon monoxide has protective and beneficial effects on a vast array of responses against multiple organ injury, inflammation, apoptosis, cell proliferation, vas

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Source Control in the ICUcua’ is a Latin aphorism that dates back to the early days of medicine, but is still widely used to stress the importance of source control. Although source control is generally considered to be the cornerstone of the management of several infections, it is also the least ‘hyped’ strategy, and there

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人類

Clarithromycin: A Promising Immunomodulator in Sepsis[.]. The high mortality rates, ranging between 35 and 50 % despite adequate antimicrobial treatment [.], have encouraged intense research efforts to better understand the mechanisms underlying the pathogenesis of sepsis. As a consequence, sepsis syndrome is now recognized as a complex entity created

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Economic and Social Burden of Severe Sepsis.–.]. For these reasons, healthcare providers, managers, government authorities, and insurance companies have focused their attention on strategies that could reduce the economic and social burden of sepsis. In the healthcare system, ICUs consume a considerable amount of resources and have frequentl

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