Titlebook: Integrin Protocols; Anthony Howlett Book 1999 Springer Science+Business Media New York 1999

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Production of Rat Monoclonal Antibodies Specific for Mouse Integrinsg specificity, function, and structure. Consequently, they have been instrumental in defining three families of adhesion receptors: the cadherin, immunoglobulin, and integrin families. Integrins include over 20 adhesion receptors that react with the extracellular matrix or cell-surface molecules. In

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Adrenaline

Assays for Kinase Activityuding increased tyrosine phosphorylation of a number of cellular proteins, elevation of phosphoinositide 3-OH kinase (PI3-K) products, and increase in intracellular calcium concentrations (.). Although integrins do not possess any intrinsic enzymatic activity, they influence the activity of cytoplas

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蔓藤圖飾

Application of Flow Cytometry in the Analysis and Sterile Sorting of Cell Populations Based on Integhe measurement of light emitted from the cells by scatter or fluorescence (.,.). Integrins have been studied by flow cytometry since the mid-1980s when immunologists started examining CD11 (integrins α., α., and α.) as markers of T-cell differentiation in mixed cell populations (.,.). These analyses

機(jī)械

Expression of Integrin Transcripts in Human Cancer Cellssed of an α and a (β chain. Integrins belong to a large family of proteins. Currently over 16 α chains and 9 β chains have been reported. The particular combination of α and β chains largely determines ligand specificity (.,.).

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Functional Analysis of the β2 Integrinsy expressed on leukocytes, are of critical importance for leukocyte functions (.–.). The discovery of an inherited defect in leukocyte adhesion (called leukocyte adhesion deficiency, LAD), caused by the lack of expression of β. integrins on the cell surface, underscored the important biological role

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Expression of Heterologous Integrin Genesociated α and β subunits (.). Integrins have been implicated in organ and tissue development, normal and aberrant cellular growth, and modulation of intracellular signal-transduction mechanisms (.–.). The expression of individual integrin subunits in mammalian systems has been instrumental in studie

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