Titlebook: Integral Clinical Investigation; An Aspect of Pananth John G. Howells Textbook 1982Latest edition John G. Howells 1982 aspect.integral.medi

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ate is generally associated with an exacerbation of the underlying liver disease. Several HDV RNA sequences are now available from different viral strains which show a relatively high conservation of sequences, although some differences are shown in some parts of the viral genome. The delta antigen

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John G. Howells the analysis of the clinical symptoms coupled with laboratory tests. Although rapid advance- ments have been made in the laboratory diagnosis of virus diseases, the neces- sary isolation of the causative virus from the clinical specimens is a relatively long procedure. Viruses which integrate into

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the fact that more than 40 malignant histological types have been described, it is reasonable to think that only specialized centers can have enough experience in managing these neoplasms. The peculiar “multidisciplinary-team” approach is mandatory in bone tumors, in order to avoid dramatic mistakes

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both sexes, suggesting that these sites of latent HPV infections might act as a reservoir for such infections. In the present review, the clinical significance of genital HPV infections is discussed. The importance of making a distinction between (1) clinically manifest, (2) subclinical, and (3) lat

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termining whether or not infection is present in patients with incomplete or absent seroreactivity or in the obligately seropositive children of seropositive mothers..Serologic reagents for the detection of these viruses, made from lysates of HILV-I-infected cells, are believed to be very sensitive

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atients with acute hepatitis and in immunocompromised subjects, where the pattern of serological HDV markers may be modified. Among these techniques, the polymerase chain reaction (PCR) appears to be very sensitive in detecting HDV RNA sequences, both in liver and in serum samples. This approach is