Titlebook: Inositol and Phosphoinositides; Metabolism and Regul John E. Bleasdale,Joseph Eichberg,George Hauser Book 1985 The Humana Press Inc. 1985 A

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Neurotransmitter Receptor-Mediated Myo-Inositol 1-Phosphate Accumulation in Hippocampal Slicese addition of lithium to the incubation medium markedly amplified the effect of all agonists in stimulating [.H]inositol 1-phosphate accumulation. The response to a number of neurotransmitter receptor agonists was dependent on the amount of tissue (mg protein), and the concentrations of lithium, and

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The Enzymology of Phosphoinositide Catabolism, with Particular Reference to Phosphatidyl-Inositol 4,terase of rat brain. We have previously shown (Irvine ., 1984a) that under approximately physiological ionic conditions, this enzyme will not hydrolyze its substrate in a lipid mixture similar to that of the inner half of a plasma membrane; however, if the substrate presentation is changed, the enzy

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Subcellular Sites of Polyphosphoinositide Metabolism in Rat Liveras important components of biological membranes, the subcellular distribution of PIP, PIP., and the enzymes involved in their metabolism have not been fully characterized. We have therefore prepared various subcellular organelles from rat liver and determined their PI kinase and PIP kinase activitie

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The , Phospholipid Synthesis Effect: Occurrence, Characteristics, Underlying Mechanisms and Function), phosphatidylinositol 4-phosphate (PIP), phosphatidylinositol 4,5-bisphosphate (PIP.) and diacylglycerol (DG) in certain of their target tissues. This effect is due to . synthesis of PA and may be the consequence of increased availability of substrate ., glycerol 3-P) or increased activity of glyc

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