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Souad El Hilali,Ahmed Azougaghlting in resistance to these drugs. At least three members of the family of human multidrug resistance-associated proteins (MRPs) (MRP4, 5, and 8) are able to transport not only the cyclic nucleotides cyclic adenosine 5′-monophosphate and cyclic guanosine 5′-monophosphate but also some nucleoside-mo

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Ne?e ?z?and?r,Sevim Ate? Canoietic malignancies. The activity of ara-C depends on the conversion to its cytotoxic triphosphate derivative, ara-CTP. This process is influenced by multiple factors, including transport, phosphorylation, deamination, and levels of competing metabolites, deoxycytidine triphosphate in particular. Fu

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Candra Triastutiningsih,Rini Rachmawatiale brain networks contribute to emotional dysregulation. Dysfunctional networks can develop as a result of epigenetic and learning based changes to the connectome. There may be no detectible structural abnormality, but rather differing patterns of connectivity leading to inefficient processing of i